Paroxetine may cause heart defects in the fetus if it is taken during early pregnancy and problems in newborns following delivery if it is taken during the last months of pregnancy
Vermetten E, Vythilingam M, Southwick SM, Charney DS, Bremner JD
This paper reviews controlled studies of the treatment of depression in elderly patients using paroxetine, a selective serotonin reuptake inhibitor
serum sodium less than 130 mmol/L (risk of exacerbating
Among these are effects on male fertility, birth defects, gestational hypertension, prolonged QT interval in infants, hyperprolactinemia, cognitive impairment
All of these factors contribute to greater anticholinergic side effects in older adults
Low sodium levels
It is also available in a liquid oral solution with each 5 mL of liquid containing 10 mg of paroxetine
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
The antidepressant drugs paroxetine and fluoxetine are potent inhibitors
26,29,30 The onset of action of paroxetine is reported to be approximately 6 weeks
Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0
, 2016)
It's often used to treat depression, and sometimes obsessive compulsive disorder (OCD), panic attacks, anxiety or post-traumatic stress disorder (PTSD)
The maximum recommended dose of paroxetine is 50mg or 60mg a day, depending on why you are taking it
Nausea, drowsiness, dizziness, trouble sleeping, loss of appetite, weakness, dry mouth, sweating, blurred vision, and yawning may occur
fast or irregular breathing
Some people may have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless
Stopping the drug abruptly may result in Four studies specified recruiting older adults or elderly participants (aged more than 65 years: Krystal 2010; Lankford 2012; 60 to 80 years: Zhou 2002; more than 50 years: Reynolds 2006)
Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder